Wear comfortable, broken-in footwear. If you feel a hot spot, stop & take off your boots. Put your feet into cold water when you get the chance to cool them.
Wicking inner socks may help prevent blisters.
Bring Leukoplast or Elastoplast bandages, duct tape & any other blister first aid products you like, just in case.
If you do get a blister, using a sterile needle, prick the blister a few times. Drain without touching the fluid or holes. Seal with liquid Betadine and, when dry, place some tape over it. We usually use duct tape it's inexpensive and seems to stay as well as anything else.
Insect Bites & Stings?
Good news. We saw none in the Colca Canyon except one scorpion minding his own business under a rock!
If you come across biting insects, especially flies, prevention is the best strategy.
Bring long pants and a long-sleeved top. Tuck pants into your socks and shirt into pants. One of our hikers swears by his light unlined nylon pants & cycling jacket.
A bigger worry is that you may get stuck with cactus needles.